منابع مشابه
Muscarinic cholinergic receptors in murine lymphocytes: demonstration by direct binding.
Using [3H]quinuclidinyl benzilate as a specific cholinergic muscarinic ligand, it has been demonstrated that lymphocytes have muscarinic binding sites. There are approximately 200 sites per cell and the dissociation constant for quinuclidinyl benzilate is approximately 1 X 10(-9) M. Quinuclidinyl benzilate receptor binding is blocked by atropine and oxotremorine.
متن کاملKisspeptin-13 ameliorates memory impairment induced by streptozotocin in male rats via cholinergic system
Introduction: Kisspeptin-13 (KP-13) is a novel endogenous factor, increases synaptic transmission and is involved in several behavioral functions such as anxiety, locomotion, epilepsy and avoidance learning. However, the role of this peptide on cognition has not been well clarified yet. Here we studied the effect of kisspeptin-13 pretreatment on spatial learning and also interaction with cholin...
متن کاملGlucocorticoids Interact with Cholinergic System in Impairing Memory Reconsolidation of an Inhibitory Avoidance Task in Mice
Introduction: Recent studies suggest that glucocorticoids modulate memory reconsolidation. Moreover, cholinergic system is involved in memory reconsolidation. Since glucocorticoids interact with brain cholinergic system in modulating memory processing, we investigated whether glucocorticoid influences on the reconsolidation of emotionally arousing training depend on the cholinergic system...
متن کاملCholinergic augmentation of lymphocyte-mediated cytotoxicity. A study of the cholinergic receptor of cytotoxic T lymphocytes.
Cholinergic agonists have previously been shown to augment the ability of sensitized lymphocytes to injure cells bearing the sensitizing alleantigens. The cholinergic receptor of the attacking lymphocyte population has been studied with pharmacological manipulation of an in vitro system that quantitates the injury mediated by sensitized attacking cells upon target cells. The data reveal that mu...
متن کاملCholinergic Receptor Sensitivity Following Pharmacological Modulation of the Immune System
Objective. To study the effect of immunomodulators on learning and memory and on cholinergic receptor sensitivity. Methods. Animals were initially treated for a period of 8 days with cyclosporine/levamisole/saline. They were then subjected to passive avoidance training and 48 hrs later, the retention test for the passive avoidance task was conducted. Twenty-four hours after the retention tests ...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 2000
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)47588-4